Koshikamide A2, a cytotoxic linear undecapeptide isolated from a marine sponge of Theonella sp.

نویسندگان

  • Takahiro Araki
  • Shigeki Matsunaga
  • Nobuhiro Fusetani
چکیده

Koshikamide A2 (2) was isolated as a cytotoxic metabolite from a marine sponge of Theonella sp. Its structure was elucidated to be a linear undecapeptide by spectroscopic and chemical methods, together with enzymatic conversion to known koshikamide A1 (1). The new peptide moderately inhibited the growth of P388 murine leukemia cells.

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عنوان ژورنال:
  • Bioscience, biotechnology, and biochemistry

دوره 69 7  شماره 

صفحات  -

تاریخ انتشار 2005